Metalation: nature's challenge in bioinorganic chemistry.

Metalation: nature's challenge in bioinorganic chemistry.
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金属化:生物无机化学中自然的挑战。

DOI:
10.1007/s00775-020-01790-3
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发表时间:
2020
期刊:
a publication of the Society of Biological Inorganic Chemistry
影响因子:
--
通讯作者:
Robinson NJ
Robinson NJ
中科院分区:
--
文献类型:
--
作者:
Robinson NJ

文献摘要

相似文献

蛋白质与金属的结合,金属化,是具有挑战性的,因为最紧密的结合金属很少是正确的。在细胞内部,正确的金属化是通过控制生物利用度以及铁和锰等复杂组合的额外机制来实现的。
The association of proteins with metals, metalation, is challenging because the tightest binding metals are rarely the correct ones. Inside cells, correct metalation is enabled by controlled bioavailability plus extra mechanisms for tricky combinations such as iron and manganese.