Genetic Location of Certain Mutations Conferring Recombination Deficiency in Escherichia coli
Genetic Location of Certain Mutations Conferring Recombination Deficiency in Escherichia coli
复制标题
导致大肠杆菌重组缺陷的某些突变的遗传定位
DOI：
10.1128/jb.97.1.244-249.1969
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发表时间：
1969
影响因子：
3.2
通讯作者：
B. Low
中科院分区：
文献类型：
--
作者：
N. Willetts;A. J. Clark;B. Low
四个突变赋予重组缺陷（recA 1，recA 13，rec-12，和rec-65）已与cysC和pheA共转导，因此，他们位于53和50之间的标准大肠杆菌的遗传图谱。这四个突变在瞬时rec+/rec−合子中表现出不同程度的表观显性，并且特定突变的表观显性程度被证明是该突变的特征，而不是原始rec突变株中其他遗传差异的反映。所有四个突变映射在类似的距离cysC和pheA，尽管不同程度的明显优势，都可能在于recA基因。
Four mutations conferring recombination deficiency (recA1, recA13, rec-12, and rec-65) have been cotransduced with cysC and pheA; consequently they lie between 53 and 50 on the standard genetic map of Escherichia coli. The four mutations show different degrees of apparent dominance in transient rec+/rec− zygotes, and the degree of apparent dominance of a particular mutation was shown to be a characteristic of that mutation, not a reflection of other genetic differences in the original rec mutant strain. All four mutations map at similar distances from cysC and pheA and, despite the different degrees of apparent dominance, all may lie in the recA gene.