CYSTIC-FIBROSIS AND MALNUTRITION
CYSTIC-FIBROSIS AND MALNUTRITION
复制标题
DOI：
10.1016/s0022-3476(79)80504-1
复制
发表时间：
1979-01-01
影响因子：
5.1
通讯作者：
LAVIN, MH
中科院分区：
文献类型：
--
作者：
CHASE, HP;LONG, MA;LAVIN, MH
囊性纤维化作为一种特殊的疾病实体，几乎半个世纪以来一直被认为与营养不良有关。营养不良在疾病过程中的重要性仍然未知，关于CF中特定营养缺乏的许多信息也是如此。患有CF的儿童的补充剂应包括额外的能量，例如脂肪或碳水化合物、一种可吸收的亚油酸、水解蛋白、水乳液中的脂溶性维生素和维生素A和E、维生素B12，可能是B族维生素和维生素C以及微量矿物质。应定期进行营养状况的常规测量，特别是在生长发育不良的儿童中，应包括3天的饮食记录和同时进行的72小时粪便脂肪测定。如果脂肪吸收不良不受胰酶控制，应考虑使用抗酸剂或西咪替丁。在适当的研究完成之前，营养在CF患者中的真正作用尚不清楚。
Cystic fibrosis as a specific disease entity has been known to be associated with malnutrition for almost half a century. The importance of the malnutrition in the disease process remains unknown, as does much information about specific nutritional deficiencies in CF. Supplements for children with CF should include extra energy as fat or carbohydrate, a form of linoleic acid that can be absorbed, hydrolyzed protein, fat-soluble vitamins with vitamins A and E in a water emulsion, vitamin B12, probably B vitamins and vitamin C, and trace minerals. Routine measurements of nutritional status, particularly in children with growth failure, should be made at regular intervals and should include a three-day diet record and a simultaneous 72-hour stool fat determination. If fat malabsorption is not controlled by pancreatic enzymes, the use of antacids or cimetidine should be considered. The true role of nutrition in patients with CF will not be known until the appropriate studies are completed.