The flowering gene SINGLE FLOWER TRUSS drives heterosis for yield in tomato
The flowering gene SINGLE FLOWER TRUSS drives heterosis for yield in tomato
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DOI：
10.1038/ng.550
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发表时间：
2010-05-01
期刊：
影响因子：
30.8
通讯作者：
Zamir, Dani
中科院分区：
文献类型：
--
作者：
Krieger, Uri;Lippman, Zachary B.;Zamir, Dani
不同品种的植物杂交经常产生具有更强活力和更高产量的杂交后代，这是一种鲜为人知的现象，称为杂种优势（1,2）。杂种优势的一个经典的未经证实的模型是显性，它以其最简单的形式假设，一个杂合基因可以提高活力（3-8）。在此，我们报道了开花激素致花素的遗传起源——单花桁架（SINGLE FLOWER TRUSS， SFT）的番茄功能缺失等位基因的杂合性可使产量提高高达60%。在不同的遗传背景和环境中，SFT杂合性产生的产量优势是强大的。我们发现，一些性状以多效性整合，以繁殖方式驱动杂种优势(9)，这些效应源于SFT拮抗剂SELF PRUNING （SP）介导的生长终止抑制。我们的发现提供了第一个单显性基因影响产量的例子，并表明单杂合突变可能提高其他农业生物的生产力。
Intercrossing different varieties of plants frequently produces hybrid offspring with superior vigor and increased yields, in a poorly understood phenomenon known as heterosis(1,2). One classical unproven model for heterosis is overdominance, which posits in its simplest form that improved vigor can result from a single heterozygous gene(3-8). Here we report that heterozygosity for tomato loss-of-function alleles of SINGLE FLOWER TRUSS (SFT), which is the genetic originator of the flowering hormone florigen, increases yield by up to 60%. Yield overdominance from SFT heterozygosity is robust, occurring in distinct genetic backgrounds and environments. We show that several traits integrate pleiotropically to drive heterosis in a multiplicative manner(9), and these effects derive from a suppression of growth termination mediated by SELF PRUNING (SP), an antagonist of SFT. Our findings provide the first example of a single overdominant gene for yield and suggest that single heterozygous mutations may improve productivity in other agricultural organisms.