Memory Predicts Changes in Depressive Symptoms in Older Adults: A Bidirectional Longitudinal Analysis

Memory Predicts Changes in Depressive Symptoms in Older Adults: A Bidirectional Longitudinal Analysis
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记忆力可预测老年人抑郁症状的变化: 双向纵向分析

DOI:
10.1093/geronb/gbr035
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发表时间:
2011-09-01
影响因子:
6.2
通讯作者:
Borders, Ashley
Borders, Ashley
中科院分区:
医学1区
文献类型:
--
作者:
Jajodia, Archana;Borders, Ashley

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目标。尽管研究表明抑郁症状和老年人的记忆表现相关,但这些变量之间的时间关联尚不清楚。本研究探讨抑郁症状是否能预测日后的记忆改变,以及记忆是否能预测日后抑郁症状的改变。样本包括来自健康与退休研究的14000多名成年人,这是一项对50岁以上美国人的健康和退休情况进行的两年一次的纵向研究。延迟回忆和抑郁症状的测量是主要的研究变量。我们纳入了年龄、性别、教育程度和血管疾病史作为协变量。使用动态变化模型和潜在差异评分,我们发现记忆表现可以预测2年后抑郁症状的变化。抑郁症状并不能预测后来的记忆变化。纳入血管健康变量减小了观察到的关系的大小,表明生物过程可能部分解释记忆对抑郁症状的影响。未来的研究应该探索生物学和心理学过程,以解释较差的记忆表现和随后的抑郁症状增加之间的联系。
Objectives. Although research indicates that depressive symptoms and memory performance are related in older adults, the temporal associations between these variables remain unclear. This study examined whether depressive symptoms predicted later memory change and whether memory predicted later change in depressive symptoms.Methods. The sample consisted of more than 14,000 adults from the Health and Retirement Study, a biannual longitudinal study of health and retirement in Americans older than age 50 years. Measures of delayed recall and depressive symptoms served as the main study variables. We included age, sex, education, and history of vascular diseases as covariates.Results. Using dynamic change models with latent difference scores, we found that memory performance predicted change in depressive symptoms 2 years later. Depressive symptoms did not predict later change in memory. The inclusion of vascular health variables diminished the size of the observed relationship, suggesting that biological processes may partially explain the effect of memory on depressive symptoms.Implications. Future research should explore both biological and psychological processes that may explain the association between worse memory performance and subsequent increases in depressive symptoms.