Physical Fitness and Physical Activity at Age 13 Years as Predictors of Cardiovascular Disease Risk Factors at Ages 15, 25, 33, and 40 Years: Extended Follow-up of the Oslo Youth Study
Physical Fitness and Physical Activity at Age 13 Years as Predictors of Cardiovascular Disease Risk Factors at Ages 15, 25, 33, and 40 Years: Extended Follow-up of the Oslo Youth Study
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DOI：
10.1542/peds.2008-1118
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发表时间：
2009-01-01
期刊：
影响因子：
8
通讯作者：
Batty, G. David
中科院分区：
文献类型：
--
作者：
Kvaavik, Elisabeth;Klepp, Knut-Inge;Batty, G. David
目标。很少有研究调查儿童体育活动和身体健康与成年后心血管疾病危险因素的关系。此外，对这些发现的解释受到方法学缺陷的阻碍。在一项基于人群的队列研究中，我们探讨了儿童体育活动和身体健康对后来心血管疾病危险因素的影响（如果有的话）。数据来自奥斯陆青年研究，这是一项始于1979年的前瞻性队列研究，邀请6所学校的1016名学生（平均年龄：13岁；范围：11-15岁）参加健康教育干预。在基线和1981年（平均年龄：15岁，范围：13-17岁）、1991年（平均年龄：25岁，范围：23-27岁）、1999年（平均年龄：33岁，范围：31-35岁）和2006年（平均年龄：40岁，范围：38-42岁）再次收集心血管疾病危险因素数据。在基线时，身体健康与BMI、三头肌皮褶厚度和血压（收缩压和舒张压；N = 716）呈负相关。这些关联也出现在15岁（N = 472）、25岁（N = 280，收缩压除外）和33岁（N = 410，仅测量BMI）的前瞻性分析中，尽管其幅度逐渐减小，但在40岁（N = 294）时消失。当人们对体育活动感兴趣时，与心血管疾病风险因素的关系就会减少。控制父母和研究成员的受教育程度对这些关联的影响很小。尽管儿童时期的身体健康似乎与成年早期的肥胖和血压呈负相关，但这些影响在中年时显著减弱。儿科2009;123: e80-e86
OBJECTIVE. Few studies have examined the association of childhood physical activity and physical fitness with cardiovascular disease risk factors in adulthood. Furthermore, interpretation of these findings is hampered by methodologic shortcomings. In a population-based cohort study, we explored the influence, if any, of childhood physical activity and physical fitness on later cardiovascular disease risk factors.METHODS. Data were taken from the Oslo Youth Study, a prospective cohort study that began in 1979, when 1016 students (mean age: 13 years; range: 11-15 years) who were attending 6 schools were invited to participate in a health education intervention. Cardiovascular disease risk factor data were collected at baseline and again in 1981 (mean age: 15 years; range: 13-17 years), 1991 (mean age: 25; range: 23-27 years), 1999 (mean age: 33; range: 31-35 years), and 2006 (mean age: 40; range: 38-42 years).RESULTS. At baseline, physical fitness was inversely related to BMI, triceps skinfold thickness, and blood pressure (systolic and diastolic; N = 716). These associations were also present in prospective analyses at ages 15 (N = 472), 25 (N = 280; except for systolic blood pressure), and 33 years (N = 410, only BMI measured)-albeit with progressively diminishing magnitude-but were lost at 40 years (N = 294). There were fewer relationships with cardiovascular disease risk factors when physical activity was the exposure of interest. Controlling for educational attainment of both the parent and the study member had little impact on these associations.CONCLUSIONS. Although childhood physical fitness seems to reveal some inverse associations with obesity and blood pressure in early adulthood, these effects diminished markedly into middle age. Pediatrics 2009;123:e80-e86