A biocatalytic hydrogenation of carboxylic acids.
A biocatalytic hydrogenation of carboxylic acids.
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DOI：
10.1039/c2cc36479d
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发表时间：
2012-11
影响因子：
4.9
通讯作者：
Y. Ni;P. Hagedoorn;Jian‐He Xu;I. Arends;F. Hollmann
中科院分区：
文献类型：
--
作者：
Y. Ni;P. Hagedoorn;Jian‐He Xu;I. Arends;F. Hollmann
超嗜热火球菌可选择性地催化多种羧酸氢化成相应的伯醇。不触及其他官能团，例如孤立的 C=C-双键。通过简单的介质工程，可以将羧酸盐还原的化学选择性针对醛。
The hyperthermophile Pyrococcus furiosus catalyses the hydrogenation of a broad range of carboxylic acids selectively to the corresponding primary alcohols. Other functional groups such as isolated C=C-double bonds are not touched. The chemoselectivity of the carboxylate reduction may be directed towards aldehydes by simple medium engineering.