Regulation of physiological processes by microRNAs in insects.
Regulation of physiological processes by microRNAs in insects.
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DOI：
10.1016/j.cois.2015.06.004
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发表时间：
2015-10-01
影响因子：
5.3
通讯作者：
Raikhel AS
中科院分区：
文献类型：
--
作者：
Lucas KJ;Zhao B;Liu S;Raikhel AS
MicroRNAs （miRNAs）是一种小的非编码RNA，通过靶向信使RNA中的位点在植物和动物的基因调控过程中起作用。在昆虫中，mirna已被证明在昆虫发育过程中调节各种生理过程，包括蜕皮、变态、卵发生、胚胎发生、行为和宿主-病原体相互作用。由于miRNA在高度分化的物种中功能的保守性，miRNA在模式生物——黑腹果蝇中的作用已经被广泛研究。然而，寻求了解miRNA在非果蝇昆虫物种中的功能已成为昆虫科学发展的趋势。在这里，我们重点介绍了miRNA在昆虫生理和发育中的功能的最新发现。
MicroRNAs (miRNAs) are small non-coding RNAs that function in gene regulatory processes in plants and animals by targeting sites within messenger RNA. In insects, miRNAs have been shown to regulate a variety of physiological processes throughout insect development, including molting, metamorphosis, oogenesis, embryogenesis, behavior and host-pathogen interactions. The roles of miRNAs in the model organism, Drosophila melanogaster, have been studied extensively due to the conserved nature of miRNA function among highly divergent species. However, seeking to understand miRNA function in non-drosophilid insect species has become a growing trend in insect science. Here, we highlight the recent discoveries regarding miRNA function in insect physiology and development.