A graphene oxide-photosensitizer complex as an enzyme-activatable theranostic agent
A graphene oxide-photosensitizer complex as an enzyme-activatable theranostic agent
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DOI：
10.1039/c2cc36297j
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发表时间：
2013-01-01
影响因子：
4.9
通讯作者：
Choi, Yongdoo
中科院分区：
文献类型：
--
作者：
Cho, Youngnam;Kim, Hyunjin;Choi, Yongdoo
开发具有高亲和性和特异性的靶点可激活的“智能”平台对于广泛的生物医学应用具有重要意义。在这里，我们试图开发一种新的酶可激活的氧化石墨烯-光敏剂复合物作为生物可调的治疗诊断剂，使其有希望用于近红外（NIR）荧光成像和光诱导癌症治疗。
The development of a target-activatable "smart" platform with high-affinity and specificity is of great importance for a wide range of biomedical applications. Here, we attempted to develop a new enzyme-activatable graphene oxide-photosensitizer complex as a biologically tunable theranostic agent, making it promising for near-infrared (NIR) fluorescence imaging and photo-induced cancer therapy.