PRECISE ESTIMATION OF THE NUMBERS OF CHRONIC CARRIERS OF SALMONELLA-TYPHI IN SANTIAGO, CHILE, AN ENDEMIC AREA
PRECISE ESTIMATION OF THE NUMBERS OF CHRONIC CARRIERS OF SALMONELLA-TYPHI IN SANTIAGO, CHILE, AN ENDEMIC AREA
复制标题
DOI：
10.1093/infdis/146.6.724
复制
发表时间：
1982-01-01
影响因子：
6.4
通讯作者：
LANATA, C
中科院分区：
文献类型：
--
作者：
LEVINE, MM;BLACK, RE;LANATA, C
作为智利圣地亚哥一项控制地方性伤寒热计划的一部分，对伤寒沙门氏菌慢性带菌者的数量进行了评估。由于有准确的人口普查数据，以及胆囊炎患者中胆道疾病患病率和伤寒沙门氏菌带菌情况的可靠数据，得以对带菌者数量进行异常精确的估算。1980年，在4264514人口中，有25019名女性和4575名男性带菌者，得出的粗患病率为每10万人中有694名带菌者。由于这一人类带菌群体数量庞大，其中包括许多40岁以下的女性，因此建议伤寒控制计划应包括对带菌者的识别，随后进行健康教育和治疗干预。
As part of a program to control endemic typhoid fever in Santiago, Chile, an assessment was made of the magnitude of the reservoir of chronic carriers of S. typhi. The availability of an accurate census and reliable data on the prevalence of biliary disease and of S. typhi carriage among persons with cholecystitis allowed an unusually precise estimate of the number of carriers. In 1980 there existed 25,019 female and 4575 male carriers in a population of 4,264,514, yielding a crude prevalence of 694 carriers/105 population. Because of the magnitude of this human reservoir, which includes many females of < 40 yr of age, it is recommended that a typhoid control program include the identification of carriers followed by health education and therapeutic interventions.