PREVALENCE AND NATURAL-HISTORY OF PROGRESSIVE SUPRANUCLEAR PALSY

PREVALENCE AND NATURAL-HISTORY OF PROGRESSIVE SUPRANUCLEAR PALSY
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DOI:
10.1212/wnl.38.7.1031
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发表时间:
1988-07-01
期刊:
影响因子:
9.9
通讯作者:
DUVOISIN, RC
DUVOISIN, RC
中科院分区:
医学1区
文献类型:
--
作者:
GOLBE, LI;DAVIS, PH;DUVOISIN, RC

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我们调查了新泽西州两个县及其附近的神经科医生和慢性护理机构,总共有799,022人,关于进行性核上性麻痹的病例。所有疑似病例均采用严格标准亲自检查。患病率为1.39/10万。新泽西州共有50例患者需要步态辅助的中位时间间隔为3.1年;视觉症状。3.9年;构音障碍,3.4岁;吞咽困难,4.4岁;需要轮椅,8.2岁;死亡,9.7年。
We surveyed neurologists and chronic care facilities in and near two New Jersey counties with a combined population of 799,022, regarding cases of progressive supranuclear palsy. All suspected cases were examined personally, using rigid criteria. The prevalence ratio was 1.39/100,000. A total of 50 New Jersey cases yielded median intervals to onset of requiring gait assistance, 3.1 years; visual symptoms. 3.9 years; dysarthria, 3.4 years; dysphagia, 4.4 years; requiring wheelchair, 8.2 years; and death, 9.7 years.