Effects of galvanic vestibular stimulation on otolithic and semicircular canal eye movements and perceived vertical
Effects of galvanic vestibular stimulation on otolithic and semicircular canal eye movements and perceived vertical
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DOI：
10.1016/s0013-4694(98)00056-x
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发表时间：
1998-09-01
期刊：
影响因子：
--
通讯作者：
Dieterich, M
中科院分区：
文献类型：
--
作者：
Zink, R;Bucher, SF;Dieterich, M
目的：本研究的目的是确定耳石和半规管的影响，电流前庭刺激增加电流强度的眼动和知觉的verticality.Methods：我们测量（1）三维眼球运动，（2）主观倾斜的周边视野，和（3）主观倾斜的中央垂直线在12名健康受试者在电流前庭刺激。A矩形，单极双耳电流施加到每个主题的mastoid.Results：阳极刺激的权利乳突导致ipsiversive紧张性眼球扭转高达5.4度，对侧倾斜的周边视野（1-9度），和一个中心垂直线（0.5-6.2度）的幅度增加，随着电流强度的增加。这反映了耳石刺激。在大多数受试者中，3 mA或更高的电流强度引起叠加在静态扭转上的轻微（水平）扭转性眼球震颤（振幅1-2度）。这反映了水平和垂直半规管刺激。A相关性被发现在3个测量参数和所施加的电流强度的量。结论：因此，在低电流强度（1-3 mA）的前庭电刺激优选地激发耳石反应，这增加了电流强度。随着高于3 mA的较高电流强度，额外的半规管反应引起的水平旋转眼球震颤叠加在静态扭转偏差的形式。垂直偏斜和眼球震颤的缺乏可以用前后半规管的反向垂直分量来解释。(C)1998爱思唯尔科学爱尔兰有限公司保留所有权利。
Objective: The aim of this study was to determine the otolithic and semicircular canal effects of galvanic vestibular stimulation with increasing current strengths on eye movements and the perception of verticality.Methods: We measured (1) 3-dimensional eye movements, (2) subjective tilt of the peripheral visual field, and (3) subjective tilt of a central vertical line in 12 healthy subjects during galvanic vestibular stimulation. A rectangular, unipolar binaural electric current was applied to each subject's mastoid.Results: Anodal stimulation of the right mastoid led to an ipsiversive tonic ocular torsion of up to 5.4 degrees, to a contralateral tilt of both the peripheral visual field (1-9 degrees), and a central vertical line (0.5-6.2 degrees) increasing in amplitude with increasing current strengths applied. This reflects otolith stimulation. In most subjects, current strengths of 3 mA or more elicited a slight (horizontal-) torsional nystagmus (amplitude 1-2 degrees) that was superimposed on static torsion. This reflects horizontal and vertical semicircular canal stimulation. A correlation was found in the amount of the 3 measured parameters and the strength of the applied current.Conclusions: Thus, galvanic vestibular stimulation at low current intensities (1-3 mA) preferably excites otolith responses, which increase with increasing current intensity. With higher current intensity above 3 mA, additional semicircular canal responses are elicited in the form of horizontal-rotatory nystagmus superimposed on static torsional deviations. The lack of a vertical deviation and nystagmus can be explained by the counterdirected vertical components of the anterior and posterior semicircular canal. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.