Angle Assessment by EyeCam, Goniophotography, and Gonioscopy
Angle Assessment by EyeCam, Goniophotography, and Gonioscopy
复制标题
DOI：
10.1097/ijg.0b013e3182183362
复制
发表时间：
2012-09-01
影响因子：
2
通讯作者：
Aung, Tin
中科院分区：
文献类型：
--
作者：
Baskaran, Mani;Perera, Shamira A.;Aung, Tin
目的：比较EyeCam （Clarity Medical Systems, Pleasanton， CA）和goniography在检测角闭合方面的差异，以gonioscopy作为参考标准。方法：在这项以医院为基础的前瞻性横断面研究中，参与者接受了由单一观察者进行的阴道镜检查，以及由不同操作人员进行的EyeCam成像和阴道镜摄影。如果不能看到后小梁网，则前房角在一个象限内被分类为闭合。蒙面观察者根据闭合象限的数量对眼睛进行分类，如果有2个或更多的闭合象限，则将眼睛分类为具有角度闭合。通过kappa统计和受试者工作特征曲线下面积比较，分析了两种方法的一致性。结果：共纳入85名受试者（85只眼），其中大部分为中国人。在38只眼（45%），40只眼（47%），40只眼（47%），40只眼（47%），在两个比较中，P = 0.69， McNemar检验)。两种成像方式对闭角诊断的一致性较高（kappa = 0.86； 95%可信区间（CI）， 0.75-0.97），而EyeCam和goniopography的一致性较差（kappa = 0.72; 95% CI, 0.57-0.87）；主要是由于鼻和颞象限缺乏一致性（kappa = 0.55至0.67）。与EyeCam相比，角膜炎的AUC相近（AUC 0.93，灵敏度94.7%，特异性91.5%,P < 0.95）。结论：EyeCam与goniography对于检测gonioscopic angle closed具有同样高的敏感性和特异性。
Purpose: To compare EyeCam (Clarity Medical Systems, Pleasanton, CA) and goniophotography in detecting angle closure, using gonioscopy as the reference standard.Methods: In this hospital-based, prospective, cross-sectional study, participants underwent gonioscopy by a single observer, and EyeCam imaging and goniophotography by different operators. The anterior chamber angle in a quadrant was classified as closed if the posterior trabecular meshwork could not be seen. A masked observer categorized the eyes as per the number of closed quadrants, and an eye was classified as having angle closure if there were 2 or more quadrants of closure. Agreement between the methods was analyzed by kappa statistic and comparison of area under receiver operating characteristic curves (AUC).Results: Eighty-five participants (85 eyes) were included, the majority of whom were Chinese. Angle closure was detected in 38 eyes (45%) with gonioscopy, 40 eyes (47%) using EyeCam, and 40 eyes (47%) with goniophotography (P = 0.69 in both comparisons, McNemar test). The agreement for angle closure diagnosis (by eye) between gonioscopy and the 2 imaging modalities was high (kappa = 0.86; 95% Confidence Interval (CI), 0.75-0.97), whereas the agreement between EyeCam and goniophotography was not as good (kappa = 0.72; 95% CI, 0.57-0.87); largely due to lack of agreement in the nasal and temporal quadrants (kappa = 0.55 to 0.67). The AUC for detecting eyes with gonioscopic angle closure was similar for goniophotography and EyeCam (AUC 0.93, sensitivity = 94.7%, specificity = 91.5%; P > 0.95).Conclusions: EyeCam and goniophotography have similarly high sensitivity and specificity for the detection of gonioscopic angle closure.