RETROGRADE-AMNESIA FOLLOWING UNILATERAL TEMPORAL LOBECTOMY
RETROGRADE-AMNESIA FOLLOWING UNILATERAL TEMPORAL LOBECTOMY
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DOI：
10.1016/0028-3932(90)90018-j
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发表时间：
1990-01-01
期刊：
影响因子：
2.6
通讯作者：
NOVELLY, RA
中科院分区：
文献类型：
--
作者：
BARR, WB;GOLDBERG, E;NOVELLY, RA
在仔细匹配的颞叶切除受试者和正常对照样本中评估远程记忆表现。左颞叶切除受试者表现出一致的远期记忆障碍模式。右颞叶切除受试者的表现与正常对照组相同。在左颞叶切除术受试者中观察到的损伤模式的特点是对过去十年的时间信息的回忆缺乏，并延伸到对事实知识的某些方面的回忆缺乏。这种疾病不能仅仅归因于语言缺陷，而且至少与近期记忆中伴随的缺陷一样严重。这些发现表明，左内侧颞区除了在近期记忆功能中发挥作用外，还可能在远程信息回忆中发挥重要作用。
Remote memory performance was assessed in a carefully matched sample of temporal lobectomy subjects and normal controls. Left temporal lobectomy subjects exhibited a consistent pattern of remote memory disturbance. Right temporal lobectomy subjects performed at the same level as normal controls. The pattern of impairment observed in left temporal lobectomy subjects was characterized by deficits in recall of chronological information from the past decade and extended to deficits in recall in some aspects of factual knowledge. The disorder could not be attributed solely to language deficits and was at least as severe as accompanying deficits in recent memory. These findings suggest that the left medial temporal region may play a significant role in recall of remote information in addition to its role in recent memory functions.