Rhabdomyolysis as a Presentation of 2019 Novel Coronavirus Disease
Rhabdomyolysis as a Presentation of 2019 Novel Coronavirus Disease
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DOI：
10.7759/cureus.7561
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发表时间：
2020-04-06
影响因子：
1.2
通讯作者：
Shabarek, Nehad
中科院分区：
文献类型：
--
作者：
Suwanwongse, Kulachanya;Shabarek, Nehad
新出现的病毒感染是全球公共卫生挑战。现代化、快速、广泛的交通工具的发展使得疫情难以控制。每个人都处于危险之中，疫情可能迅速演变为大流行危机，就像我们目前面临的2019年新型冠状病毒病（COVID-19）一样。需要及时诊断病例，以改善患者的预后和控制疫情。COVID-19的常见表现包括发热、咳嗽、呼吸困难和不适。然而，患者可能会出现非典型症状，这对诊断提出了挑战。我们报告了第一例老年男性，他表现为横纹肌溶解症，后来被诊断为COVID-19。临床医生应该意识到，横纹肌溶解症可能是COVID-19的初始表现，也可能在疾病过程中的任何时间发生。横纹肌溶解症患者应接受积极的液体管理，以防止急性肾损伤（阿基）。然而，COVID-19患者存在因液体超负荷而导致氧合恶化和急性低氧性呼吸衰竭的风险。因此，在患有横纹肌溶解症的COVID-19患者中需要谨慎补液。
An emerging viral infection is a global public health challenge. The development of modern, fast, and extensive transportation makes the outbreak hard to contain. Everyone is at risk, and the outbreak can rapidly turn into a pandemic crisis, like what we are currently facing for the 2019 novel coronavirus disease (COVID-19). Prompt diagnosis of the case is required to improve patients' prognosis and control of the outbreak. The common manifestations of COVID-19 include fever, cough, dyspnea, and malaise. However, patients may present with atypical symptoms that pose a diagnostic challenge. We report the first case of an elderly male who presented with rhabdomyolysis and later was diagnosed with COVID-19. Clinicians should be aware that rhabdomyolysis can be an initial presentation of COVID-19 or can occur at any time during the disease course. Patients with rhabdomyolysis should receive aggressive fluid administration to prevent acute kidney injury (AKI). However, COVID-19 patients are at risk of worsening oxygenation and acute hypoxemic respiratory failure from fluid overload. Therefore, cautious fluid administration is needed in COVID-19 patients with rhabdomyolysis.