TGF-BETA ACCELERATED THE OSTEOGENIC DIFFERENTIATION OF BONE-MARROW CELLS INDUCED BY COLLAGEN MATRIX
TGF-BETA ACCELERATED THE OSTEOGENIC DIFFERENTIATION OF BONE-MARROW CELLS INDUCED BY COLLAGEN MATRIX
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DOI:
10.1006/bbrc.1995.1923
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发表时间:
1995-06-26
影响因子:
3.1
通讯作者:
KUBOKI, Y
中科院分区:
文献类型:
--
作者:
MIZUNO, M;KUBOKI, Y
Bone marrow cells have multipotency for differentiation. Recently we found that type I collagen matrix induced the osteogenic differentiation of bone marrow cells. In this study we showed that TGF-beta enhanced the effect of collagen matrix on bone marrow cells and accelerated the osteogenic differentiation. These results imply that TGF-beta might play a crucial role in the osteogenic differentiation of bone marrow cells during embryogenesis and the repair of bone. (C) 1995 Academic Press, Inc.