A proposed minimum skill set for university graduates to meet the informatics needs and challenges of the "-omics" era.
A proposed minimum skill set for university graduates to meet the informatics needs and challenges of the "-omics" era.
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DOI：
10.1186/1471-2164-10-s3-s36
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发表时间：
2009-12-03
期刊：
影响因子：
4.4
通讯作者：
Ranganathan S
中科院分区：
文献类型：
--
作者：
Tan TW;Lim SJ;Khan AM;Ranganathan S
高通量实验技术的发展催生了“组学”时代，在这个时代，用于各种细胞和分子现象的系统级测量的TB级数据集在数据处理和生物学意义的提取方面提出了相当大的挑战。此外，它还创造了一个尚未得到满足的需求，即有效地整合这些数据集，以实现对生物系统的洞察。它在增加了对能够与生物学家互动的生物信息学专家的需求的同时，也提高了对生物学家拥有生物信息学的基本能力并与这些专家进行无缝沟通的要求。这可以通过在他们的本科和研究生生命科学教育中嵌入生物信息学的基本培训来实现，这些培训旨在获得最低限度的计算和信息学技能。在以往努力确定适合解决生物信息学能力差距的课程的基础上，在2008年和2009年的生物信息学和计算生物学教育讲习班(WEBCB)期间采取了一项举措，以确定培训未来具有信息学能力的生物信息学家和分子生物学家的最低技能。建议的最低技能组合本质上是跨学科的，涉及生物、计算机科学、数学和统计领域的知识和熟练程度，并可根据需要量身定做。建议的生物信息学最低技能集作为大学本科生和研究生生物课程设计和开发的指导方针。
The development of high throughput experimental technologies have given rise to the "-omics" era where terabyte-scale datasets for systems-level measurements of various cellular and molecular phenomena pose considerable challenges in data processing and extraction of biological meaning. Moreover, it has created an unmet need for the effective integration of these datasets to achieve insights into biological systems. While it has increased the demand for bioinformatics experts who can interface with biologists, it has also raised the requirement for biologists to possess a basic capability in bioinformatics and to communicate seamlessly with these experts. This may be achieved by embedding in their undergraduate and graduate life science education, basic training in bioinformatics geared towards acquiring a minimum skill set in computation and informatics. Based on previous attempts to define curricula suitable for addressing the bioinformatics capability gap, an initiative was taken during the Workshops on Education in Bioinformatics and Computational Biology (WEBCB) in 2008 and 2009 to identify a minimum skill set for the training of future bioinformaticians and molecular biologists with informatics capabilities. The minimum skill set proposed is cross-disciplinary in nature, involving a combination of knowledge and proficiency from the fields of biology, computer science, mathematics and statistics, and can be tailored to the needs of the "-omics". The proposed bioinformatics minimum skill set serves as a guideline for biology curriculum design and development in universities at both the undergraduate and graduate levels.