Category-specific cortical activity precedes retrieval during memory search
Category-specific cortical activity precedes retrieval during memory search
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DOI：
10.1126/science.1117645
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发表时间：
2005-12-23
期刊：
影响因子：
56.9
通讯作者：
Norman, KA
中科院分区：
文献类型：
--
作者：
Polyn, SM;Natu, VS;Norman, KA
在这里，我们描述了一项针对人类在自由回忆任务期间进行记忆搜索的功能磁共振成像研究。通过模式分类算法识别与三类图片（面部、位置和物体）研究相关的皮层活动模式。该算法用于跟踪回忆期间这些活动模式的再现。给定类别的活动模式的再现与对该类别进行的口头回忆相关，并且在回忆事件之前几秒钟。这一结果与类别特定活动提示记忆系统检索所研究项目的假设是一致的。
Here we describe a functional magnetic resonance imaging study of humans engaged in memory search during a free recall task. Patterns of cortical activity associated with the study of three categories of pictures (faces, locations, and objects) were identified by a pattern-classification algorithm. The algorithm was used to track the reappearance of these activity patterns during the recall period. The reappearance of a given category's activity pattern correlates with verbal recalls made from that category and precedes the recall event by several seconds. This result is consistent with the hypothesis that category-specific activity is cueing the memory system to retrieve studied items.