Trends in Mortality From All Causes and Cardiovascular Disease Among Hypertensive and Nonhypertensive Adults in the United States
Trends in Mortality From All Causes and Cardiovascular Disease Among Hypertensive and Nonhypertensive Adults in the United States
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DOI：
10.1161/circulationaha.110.005645
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发表时间：
2011-04-26
期刊：
影响因子：
37.8
通讯作者：
Ford, Earl S.
中科院分区：
文献类型：
--
作者：
Ford, Earl S.
背景-美国高血压患者死亡率的趋势知之甚少。本研究的目的是检查在美国有和没有高血压的人群中全因死亡率的变化，以及这种变化是否因性别或种族而异。方法和结果-来自10852名年龄在25至74岁的国家健康和营养检查调查（NHANES）I流行病学随访研究的参与者的数据（1971年至1975年）和12 420名参与者的NHANES III关联死亡率研究（1988年至1994年）。平均随访时间分别为17.5年和14.2年。在每个队列中，高血压成人的死亡率高于非高血压成人，高血压男性高于高血压女性，高血压黑人高于高血压白人。在所有高血压参与者中，NHANES I和NHANES III的年龄校正死亡率分别为18.8/1000人年和14.3/1000人年（非高血压参与者分别为13.3和9.1/1000人年）。男性高血压患者的降低率（7.7/1000人-年; 95%可信区间，5.2 ~ 10.2）超过女性高血压患者（1.9/1000人-年; 95%可信区间，[-0.4至4.2]）（P
Background-Little is known about trends in the mortality rate among people with hypertension in the United States. The objective of the present study was to examine the change in the all-cause mortality rate among people with and without hypertension in the United States and whether any such changes differed by sex or race.Methods and Results-Data from 10 852 participants aged 25 to 74 years of the National Health and Nutrition Examination Survey (NHANES) I Epidemiological Follow-Up Study (1971 to 1975) and of 12 420 participants of the NHANES III Linked Mortality Study (1988 to 1994) were used. The mean follow-up times were 17.5 and 14.2 years, respectively. In each cohort, the mortality rate was higher among hypertensive adults than nonhypertensive adults, among hypertensive men than hypertensive women, and among hypertensive blacks than hypertensive whites. Among all hypertensive participants, the age-adjusted mortality rate was 18.8 per 1000 person-years for NHANES I and 14.3 for NHANES III (13.3 and 9.1 per 1000 person-years for nonhypertensive participants, respectively). The reduction among hypertensive men (7.7 per 1000 person-years; 95% confidence interval, 5.2 to 10.2) exceeded that among hypertensive women (1.9 per 1000 person-years; 95% confidence interval, [-0.4 to 4.2]) (P