Evaluation of the efficacy of bendiocarb in indoor residual spraying against pyrethroid resistant malaria vectors in Benin: results of the third campaign
Evaluation of the efficacy of bendiocarb in indoor residual spraying against pyrethroid resistant malaria vectors in Benin: results of the third campaign
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DOI：
10.1186/1756-3305-5-163
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发表时间：
2012-08-08
影响因子：
3.2
通讯作者：
Akogbeto, Martin
中科院分区：
文献类型：
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作者：
Osse, Razaki;Aikpon, Rock;Akogbeto, Martin
背景：自2008年以来，国家疟疾控制规划（NMCP）一直在贝宁开展室内滞留喷洒（IRS）工作。第一轮和第二轮行动取得了成功，在实施室内规划的地区，疟疾传播大幅减少。我们在此公布第三轮选举的结果。本研究的目的是将第三轮IRS的结果与前两轮IRS的结果进行比较。国内回收站的第二次成功将使贝宁政府能够将该战略扩展到其他领域。方法：在韦梅省4个区家庭进行蚊虫采集，并对蚊虫进行灭虫威处理。在这些地区，超过35万居民受到IRS的保护。第五个未经治疗的地区作为对照。在这5个区组织了蚊虫收集，以跟踪疟疾传播的动态和蚊子行为的可能变化。结果：第3轮室内灌吸后，居民叮人率明显下降，其中阿卓侯（89.78%）、当波（56.8%）和米塞雷特（93.22%）居民叮人次数少于2次；每晚冈比亚。与此同时，所有干预区昆虫接种率（EIR）均显著下降，降幅达74.26%。我们还注意到虫媒的寿命、吸血率和苯虫威对安家蝇的致害性显著降低。结论：本研究再次证明了苯虫威对拟除虫菊酯抗性的按蚊种群有效。本品可推荐与其他杀虫剂联合使用，以管理病媒对杀虫剂的抗药性。
Background: Since 2008, the National Malaria Control Program (NMCP) has been engaged in the implementation of indoor residual spraying (IRS) in Benin. The first and second round was a success with a drastic decrease of malaria transmission in areas under IRS. We present here the results of the third round. The purpose of this study was to compare the results of the third round of IRS to those achieved during the first two rounds. A second success of IRS will enable the Government of Benin to extend the strategy to other areas.Methods: Mosquito collections were carried out in the department of Oueme where the homes of four districts were treated with bendiocarb. In these districts, more than 350 000 inhabitants were protected by IRS. A fifth untreated district served as control. In the five districts, mosquito collections were organized to follow the dynamics of malaria transmission and possible changes in the behavior of mosquitoes.Results: A significant reduction in human biting rate was recorded after the third round of IRS, specifically in Adjohoun (89.78%), Dangbo (56.8%) and Misserete (93.22%) where an inhabitant received less than 2 bites of An. gambiae per night. During this same time, the entomological inoculation rate (EIR) declined dramatically in all areas under intervention (74.26% reduction). We also noted a significant reduction in longevity, the blood feeding rate of the vectors and an increase in exophily induced by bendiocarb on An. gambiae and Mansonia spp.Conclusion: The present study showed, once again, the effectiveness of bendiocarb on anopheles populations resistant to pyrethroids. This product can be recommended in combination with other insecticides for the management of vector resistance to insecticides.