Intermuscular adipose tissue-free skeletal muscle mass: estimation by dual-energy X-ray absorptiometry in adults
Intermuscular adipose tissue-free skeletal muscle mass: estimation by dual-energy X-ray absorptiometry in adults
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DOI：
10.1152/japplphysiol.00260.2004
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发表时间：
2004-08-01
影响因子：
3.3
通讯作者：
Heymsfield, SB
中科院分区：
文献类型：
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作者：
Kim, J;Heshka, S;Heymsfield, SB
骨骼肌（SM）是一个大的和生理上重要的隔室。发现脂肪组织散布在SM组之间和SM组内，并且被称为肌间脂肪组织（IMAT）。本研究的目的是建立预测模型，将双能X线吸收法（DXA）估计的无脂肪软组织（ALST）与磁共振成像量化的全身无IMAT SM联系起来。在270名健康成年人[体重指数（BMI）为16 kg/m2]中评估了ALST和全身无IMAT SM，但未在BMI < 16 kg/m2的人群中评估（n = 12）。DXA为基础的模型是准确的预测IMAT免费SM在选定的人群中，从而提供了一个新的机会，量化SM的生理和流行病学调查。
Skeletal muscle (SM) is a large and physiologically important compartment. Adipose tissue is found interspersed between and within SM groups and is referred to as intermuscular adipose tissue (IMAT). The study objective was to develop prediction models linking appendicular lean soft tissue (ALST) estimates by dual-energy X-ray absorptiometry (DXA) with whole body IMAT-free SM quantified by magnetic resonance imaging. ALST and total-body IMAT-free SM were evaluated in 270 healthy adults [body mass index (BMI) of 16 kg/m(2)) but not in those with a BMI of < 16 kg/m(2) (n = 12). The DXA-based models are accurate for predicting IMAT-free SM in selected populations and thus provide a new opportunity for quantifying SM in physiological and epidemiological investigations.