Determination of Trace Perfluoroalkyl Carboxylic Acids in Edible Crop Matrices: Matrix Effect and Method Development.
Determination of Trace Perfluoroalkyl Carboxylic Acids in Edible Crop Matrices: Matrix Effect and Method Development.
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DOI：
10.1021/acs.jafc.7b02677
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发表时间：
2017-09
影响因子：
6.1
通讯作者：
L. Xiang;Lei Chen;Tao Xiao;C. Mo;Yan-Wen Li;Q. Cai;Hui Li;Dong-mei Zhou;M. Wong
中科院分区：
文献类型：
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作者：
L. Xiang;Lei Chen;Tao Xiao;C. Mo;Yan-Wen Li;Q. Cai;Hui Li;Dong-mei Zhou;M. Wong
建立了超声波提取-固相萃取净化-高效液相色谱-串联质谱（HPLC-MS/MS）同时测定谷物、根菜类蔬菜（胡萝卜）、叶菜类蔬菜（生菜）和瓜类蔬菜（南瓜）中9种全氟烷基羧酸（PFCAs）的方法。对萃取剂和净化柱的种类、Supelclean石墨化炭的使用、基质效应及其潜在影响因素进行了评价，以获得最佳萃取工艺。该方法具有较高的灵敏度和准确度，方法的检测限和回收率在4个强化水平在各种基质中的范围从0.017到0.180 ng/g（干重）和从70%到114%。该方法成功应用于多个农场不同农作物样品中全氟乙酸的测定，证明了该方法对真实的农作物中全氟乙酸定期监测的实用性。
A robust method was developed for simultaneous determination of nine trace perfluoroalkyl carboxylic acids (PFCAs) in various edible crop matrices including cereal (grain), root vegetable (carrot), leafy vegetable (lettuce), and melon vegetable (pumpkin) using ultrasonic extraction followed by solid-phase extraction cleanup and high liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). The varieties of extractants and cleanup cartridges, the usage of Supelclean graphitized carbon, and the matrix effect and its potential influencing factors were estimated to gain an optimal extraction procedure. The developed method presented high sensitivity and accuracy with the method detection limits and the recoveries at four fortification levels in various matrices ranging from 0.017 to 0.180 ng/g (dry weight) and from 70% to 114%, respectively. The successful application of the developed method to determine PFCAs in various crops sampled from several farms demonstrated its practicability for regular monitoring of PFCAs in real crops.