Traces of human migrations in Helicobacter pylori populations
Traces of human migrations in Helicobacter pylori populations
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DOI：
10.1126/science.1080857
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发表时间：
2003-03-07
期刊：
影响因子：
56.9
通讯作者：
Suerbaum, S
中科院分区：
文献类型：
--
作者：
Falush, D;Wirth, T;Suerbaum, S
幽门螺杆菌是人类的慢性胃病原体，可以分为七个人群，并具有不同地理分布的亚群。这些现代人口从非洲，中亚和东亚出现的祖先人群中获得基因库。随后的传播可以归因于人类的迁徙通量，例如波利尼西亚和美洲的史前殖民化，新石器时代的耕种引入欧洲，非洲内部的班图邦的扩张以及山地贸易。
Helicobacter pylori, a chronic gastric pathogen of human beings, can be divided into seven populations and subpopulations with distinct geographical distributions. These modern populations derive their gene pools from ancestral populations that arose in Africa, Central Asia, and East Asia. Subsequent spread can be attributed to human migratory fluxes such as the prehistoric colonization of Polynesia and the Americas, the neolithic introduction of farming to Europe, the Bantu expansion within Africa, and the stave trade.