Comparison between broadband and monochromatic photopic negative response in full-field electroretinogram in controls and subjects with primary open-angle glaucoma
Comparison between broadband and monochromatic photopic negative response in full-field electroretinogram in controls and subjects with primary open-angle glaucoma
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DOI：
10.1007/s10633-018-09668-1
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发表时间：
2019-02-01
影响因子：
1.4
通讯作者：
Sen, Parveen
中科院分区：
文献类型：
--
作者：
Banerjee, Aniruddha;Khurana, Mona;Sen, Parveen
目的通过前瞻性、横断面、病例对照研究，探讨全视场闪烁视网膜电图（ERG）宽带和单色光负反应（PhNR）在评价原发性开角型青光眼（POAG）患者神经节细胞损伤中的作用。方法从印度南部一家三级眼科保健中心门诊招募POAG患者和年龄匹配的正常人。共招募了25名POAG患者和50名年龄匹配的正常受试者。采用宽带(在10cd/m（2)白色背景下的3.5 ccd .s/m(2)白色刺激）和单色(在10cd/m(2)蓝色背景下的3.5 ccd .s/m(2)红色刺激和10cd/m（2)黄色背景下的1 ccd .s/m(2)蓝色刺激）记录ERG。结果与正常人相比，POAG组的PhNR幅度下降幅度更大，红-蓝PhNR [26.37 mu V；p
PurposeA prospective, cross-sectional, case-control study was conducted to investigate the role of broadband and monochromatic photopic negative response (PhNR) of the full-field flash electroretinogram (ERG) in the evaluation of ganglion cell damage in primary open-angle glaucoma (POAG) subjects.MethodsSubjects with POAG and age-matched normal subjects were recruited from the outpatient department of a tertiary eye care center in South India. A total of 25 patients with POAG and 50 age-matched normal subjects were recruited. ERG was recorded using broadband (3.5cd.s/m(2) white stimulus on 10cd/m(2) white background) and monochromatic (3.5cd.s/m(2) red stimulus on 10cd/m(2) blue background and 1cd.s/m(2) blue stimulus on 10cd/m(2) yellow background) stimuli.ResultsThe reduction in PhNR amplitude in POAG compared to normal individuals was higher in red-on-blue PhNR [26.37 mu V; p