5-HT2A promoter polymorphism-1438G/A, anorexia nervosa, and obsessive-compulsive disorder
5-HT2A promoter polymorphism-1438G/A, anorexia nervosa, and obsessive-compulsive disorder
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DOI：
10.1016/s0140-6736(05)78746-8
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发表时间：
1998-06-13
期刊：
影响因子：
168.9
通讯作者：
Goldman, D
中科院分区：
文献类型：
--
作者：
Enoch, MA;Kaye, WH;Goldman, D
提出了一项研究，复制了一个协会的5-HT.. -受体启动子多态性，-1438G/A，与神经性厌食症和强迫症。对三组无关的白色人进行多态性基因分型的方法;数据表明启动子多态性可能有助于行为特征，如完美主义或强迫症。
Presents a study that replicates an association of a 5-HT..-receptor promoter polymorphism,-1438G/A, with anorexia nervosa and obsessive-compulsive disorder. Method of genotyping three independent sets of unrelated white people for the polymorphism; Data suggesting the promoter polymorphism may contribute to a behavioural trait, such as perfectionism or obsessionality.