Examining noise sources at the single-molecule level:: 1/f noise of an open maltoporin channel
Examining noise sources at the single-molecule level:: 1/f noise of an open maltoporin channel
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DOI：
10.1103/physrevlett.85.202
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发表时间：
2000-07-03
影响因子：
8.6
通讯作者：
Winterhalter, M
中科院分区：
文献类型：
--
作者：
Bezrukov, SM;Winterhalter, M
我们研究了1/f噪声的现象学起源的溶质特异性细菌内通道，麦芽孔蛋白。我们表明，切除后的小，但可分辨的逐步变化的记录中的电流通过一个单一的开放通道，1/f噪声分量消失，通道表现出噪声是“白色”低于100 Hz。结合最近几个细菌孔蛋白的噪声研究的结果，我们的观察表明，1/f噪声是由平衡电导波动有关的通道孔结构成分的构象灵活性。
We have studied the phenomenological origin of 1/f noise in a solute-specific bacterial inn channel, maltoporin. We show that after excision of small, but resolvable stepwise changes in the recordings of the current through a single open channel, the 1/f noise component disappears and the channel exhibits noise that is "white" below 100 Hz. Combined with results of a recent noise study of several bacterial porins, our observations suggest that 1/f noise is caused by the equilibrium conductance fluctuations related to the conformational flexibility of the channel pore structural constituents.