The effect of massage on immune function and stress in women with breast cancer - A randomized controlled trial
The effect of massage on immune function and stress in women with breast cancer - A randomized controlled trial
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DOI：
10.1016/j.autneu.2009.03.010
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发表时间：
2009-10-05
影响因子：
2.7
通讯作者：
Stener-Victorin, E.
中科院分区：
文献类型：
--
作者：
Billhult, A.;Lindholm, C.;Stener-Victorin, E.
目的：通过研究乳腺癌患者外周血自然杀伤（NK）细胞的数量和活性，与对照组相比，检查轻压擦除对循环淋巴细胞的短期影响。此外，还研究了轻度压力冲洗对唾液皮质醇水平、心率和血压的影响。设计图：单中心，前瞻性，随机和对照study.Methods：30名妇女，年龄在50至75岁（平均61 SD = 7.2）与乳腺癌接受放射治疗在瑞典西南部的一家医院参加了这项研究。他们被分配接受全身轻压按摩治疗的形式，或控制访问，他们得到了同等的关注。在按摩/对照访视前后采集血液样本、唾液、心率和血压记录。组间随时间变化的差异进行了分析学生的t检验结果：轻压effleurage按摩减少了放射治疗过程中发生的NK细胞活性的恶化。此外，它降低了心率和收缩压。没有影响被证明对皮质醇和舒张压。结论：一个单一的全身轻压effleurage按摩有一个短期的影响NK细胞活性，收缩压和心率在乳腺癌患者。然而，这些发现的长期临床意义需要进一步研究。(C)2009爱思唯尔有限公司版权所有。
Objectives: To examine the short-term effects of light pressure effleurage on circulating lymphocytes by studying the number and activity of peripheral blood natural killer (NK) cells in patients with breast cancer compared to a control group. Furthermore, the effect of light pressure effleurage on salivary cortisol levels, heart rate and blood pressure was studied. Design: Single centre, prospective, randomized and controlled study.Methods: Thirty women, aged 50 to 75 years (mean 61 sd = 7.2) with breast cancer undergoing radiation therapy in a hospital in southwestern Sweden were enrolled in the study. They were allocated to either receive massage in the form of a full-body light pressure effleurage treatment, or a control visit where they were given an equal amount of attention. Blood samples, saliva, notation of heart rate and blood pressure were collected before and after massage/control visit. Differences in change over time between groups were analyzed by Student's t-testResults: Light pressure effleurage massage decreased the deterioration of NK cell activity occurring during radiation therapy. Furthermore it lowered heart rate and systolic blood pressure. No effects were demonstrated on cortisol and diastolic pressure.Conclusions: A single full-body light pressure effleurage massage has a short-term effect on NK cell activity, systolic blood pressure and heart rate in patients with breast cancer. However, the long-term clinical importance of these findings needs to be further investigated. (C) 2009 Elsevier B.V. All rights reserved.