Facile Synthesis of Polysubstituted Oxazoles via A Copper-Catalyzed Tandem Oxidative Cyclization
Facile Synthesis of Polysubstituted Oxazoles via A Copper-Catalyzed Tandem Oxidative Cyclization
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通过铜催化串联氧化环化轻松合成多取代恶唑
DOI：
10.1021/ol100688c
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发表时间：
2010-05-21
期刊：
影响因子：
5.2
通讯作者：
Wang, Zhiyong
中科院分区：
文献类型：
--
作者：
Wan, Changfeng;Zhang, Jintang;Wang, Zhiyong
通过铜催化串联氧化环化开发了多取代恶唑的高效合成。所需的产物可以在温和的条件下从容易获得的起始原料获得。这是合成恶唑衍生物的一种有吸引力的替代方法。
A highly efficient synthesis of polysubstituted oxazoles was developed via a copper-catalyzed tandem oxidative cyclization. The desired products can be obtained from readily available starting materials under mild conditions. This is an attractive alternative method for the synthesis of oxazole derivatives.