Standards for PET Image Acquisition and Quantitative Data Analysis
Standards for PET Image Acquisition and Quantitative Data Analysis
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DOI：
10.2967/jnumed.108.057182
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发表时间：
2009-05-01
影响因子：
9.3
通讯作者：
Boellaard, Ronald
中科院分区：
文献类型：
--
作者：
Boellaard, Ronald
F-18-FDG PET在肿瘤学诊断、预后判断和疗效监测中的作用日益受到重视。然而，以标准化摄取值(SUV)为例的PET定量受到许多技术和生理因素的影响。因此，文献中关于基于SUV的患者预后的一些差异可以用F-18-FDG PET研究方法的不同来解释。为了了解影响PET定量的因素，已经进行了各种技术和临床研究。在这些研究结果的基础上，提出了一些建议和指导方针，目的是改善F-18-FDG PET研究的图像质量和定量准确性。在这篇文章中，提供了肿瘤学定量F-18-FDG PET研究的建议和指南的概述。特别注意某些建议所依据的理由以及各种准则中的一些差异。
F-18-FDG PET is increasingly being recognized as an important tool for diagnosis, determination of prognosis, and response monitoring in oncology. However, PET quantification with, for example, standardized uptake values (SUVs) is affected by many technical and physiologic factors. As a result, some of the variations in the literature on SUV-based patient outcomes are explained by differences in F-18-FDG PET study methods. Various technical and clinical studies have been performed to understand the factors affecting PET quantification. On the basis of the results of those studies, several recommendations and guidelines have been proposed with the aims of improving the image quality and the quantitative accuracy of F-18-FDG PET studies. In this contribution, an overview of recommendations and guidelines for quantitative F-18-FDG PET studies in oncology is provided. Special attention is given to the rationale underlying certain recommendations and to some of the differences in various guidelines.