Protein and carbohydrate selection respond to changes in dietary saturated fatty acids but not to changes in essential fatty acids.
Protein and carbohydrate selection respond to changes in dietary saturated fatty acids but not to changes in essential fatty acids.
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蛋白质和碳水化合物的选择对膳食饱和脂肪酸的变化做出反应，但对必需脂肪酸的变化没有反应。
DOI：
10.1016/0024-3205(90)90567-b
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发表时间：
1990
期刊：
影响因子：
6.1
通讯作者：
C. Greenwood
中科院分区：
文献类型：
--
作者：
C. McGee;C. Greenwood
我们之前报道了断奶后大鼠饲喂牛油或豆油的蛋白质和碳水化合物选择模式的差异。设计了两个实验来确定介导选择行为的膳食脂肪特性。每组试验中，饲粮脂肪占饲粮的20% (w/w)，通过混合脂肪源获得脂肪酸谱。大鼠被随机分配到只有脂肪酸组成不同的饮食中（24%蛋白质，40%碳水化合物）。2周后，从两种脂肪组成的饲料中选择大鼠，但蛋白质和碳水化合物组成不同（55%蛋白质，4%碳水化合物和5%蛋白质，61%碳水化合物）。试验1旨在检验必需脂肪酸的相对（ω6:ω3比值为1和20）和绝对（ω6比值为15%或4%、ω3比值为0.7%或0.2%）差异对宏量营养素选择模式的影响。不同的膳食必需脂肪酸对能量摄入和以蛋白质和碳水化合物形式消耗的能量比例没有影响。实验2考察了饱和脂肪水平（3-10%日粮（w/w））的差异对蛋白质和碳水化合物选择的影响。选择高饱和脂肪饮食的动物比选择低饱和脂肪饮食的大鼠消耗更多的蛋白质能量和更少的碳水化合物能量（p< 0.0001）。回归分析用于检验蛋白质或碳水化合物能量百分比与膳食脂肪类别之间的关系。饲粮饱和脂肪百分比与蛋白质百分比或碳水化合物能量百分比之间的相关性最强（p< 0.0001）。多不饱和脂肪比与蛋白质和碳水化合物能量百分比也呈弱相关（p< 0.05）。多不饱和脂肪酸、单不饱和脂肪酸、ω6和ω3脂肪酸与蛋白质和碳水化合物能量百分比无显著相关。这些结果表明，蛋白质和碳水化合物的选择模式会随着膳食脂肪酸质的不同而改变，而膳食中饱和脂肪的含量是膳食脂肪介导行为改变的重要特征。
We previously reported differences in protein and carbohydrates selection patterns in post-weanling rats fed beef tallow or soybean oil-based diets. Two experiments were designed to determine the characteristic of the dietary fat which mediates the selection behavior. For each experiment, dietary fat was 20% (w/w) of diets and fatty acid profiles were obtained by blending fat sources. Rats were randomly assigned to diets (24% protein, 40% carbohydrate) which varied only in fatty acid composition. After 2 weeks, rats selected from 2 diets with the fat composition previously fed, but varying in their protein and carbohydrate composition (55% protein, 4% carbohydrate and 5% protein, 61% carbohydrate). Experiment 1 was designed to test the effect of relative (ω6:ω3 ratios of 1 and 20) and absolute (15% or 4% ω6, 0.7% or 0.2% ω3) differences in essential fatty acids on macronutrient selection patterns. Differences in dietary essential fatty acids had no effect on energy intake or the proportion of energy consumed as protein and carbohydrate. Experiment 2 examined the effect of differences in the level of saturated fat (3–10% diet (w/w)) on protein and carbohydrate selection. Animals selecting from diets with higher levels of saturated fat consumed more energy as protein and less as carbohydrate than rats selecting from diets with lower levels of saturated fat (p< 0.0001). Regression analysis was used to examine the relationship between percent protein or carbohydrate energy and classes of dietary fat. The strongest relationship existed between percent dietary saturated fat and percent protein or carbohydrate energy (p< 0.0001). Polyunsaturated:saturated fat ratio was also weakly associated with percent protein and carbohydrate energy (p< 0.05). Polyunsaturated, monounsaturated, ω6 and ω3 fatty acids were not significantly related to percent protein or carbohydrate energy. These results indicated that protein and carbohydrate selection patterns are altered in response to qualitatively different dietary fatty acids, and that the amount of saturated fat in the diet is the important characteristic of dietary fat mediating the behavioral alteration.
膳食 (n-3) 脂肪酸补充剂对大鼠淋巴细胞和肝微粒体脂质动态和组成的影响。
DOI：
10.1016/0005-2736(86)90454-2
发表时间：
1986
期刊：
Biochimica et biophysica acta
影响因子：
--
作者：
Conroy,DM;Stubbs,CD;Belin,J;Pryor,CL;Smith,AD
通讯作者：
Smith,AD