Pressure To Be Thin and Insulin Sensitivity Among Adolescents.
Pressure To Be Thin and Insulin Sensitivity Among Adolescents.
复制标题
青少年的瘦身压力和胰岛素敏感性。
DOI：
10.1016/j.jadohealth.2015.09.010
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发表时间：
2016
期刊：
影响因子：
--
通讯作者：
Yanovski,JackA
中科院分区：
文献类型：
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作者：
Schvey,NatashaA;Shomaker,LaurenB;Kelly,NicholeR;Pickworth,CourtneyK;Cassidy,Omni;Galescu,Ovidiu;Demidowich,AndrewP;Brady,SheilaM;Tanofsky-Kraff,Marian;Yanovski,JackA
PurposeExtant research indicates that some of the comorbidities associated with adult obesity may be adversely affected by the stress resulting from negative body image and weight-related stigma. This study examined the association between weight-related pressure and insulin sensitivity in adolescents, who are vulnerable to both weight-based teasing and the onset of metabolic dysregulation.MethodsParticipants were 215 adolescent healthy volunteers (55% female; 59% white; 35% overweight/obese; mean ± standard deviation age = 15.4 ± 1.4 year), who completed a self-report measure of pressure to be thin from parents, friends, and romantic partners. Fasting blood samples were obtained to assess serum insulin and glucose, which were used to calculate insulin sensitivity; fat mass (kg) and fat-free mass (%) were measured with air-displacement plethysmography. Pubertal stage was determined by physical examination.ResultsPressure to be thin was positively associated with fasting insulin (p= .01) and negatively associated with insulin sensitivity (p= .02), after controlling for pubertal stage, sex, race, height, fat-free mass, and adiposity. Pressure to be thin was associated with a greater odds of having hyperinsulinemia (fasting insulin ≥ 15 μIU/mL; odds ratio (95% confidence interval): 1.65 [1.08–2.50],p= .02), adjusting for the same covariates.ConclusionsResults indicate that adolescents perceiving more pressure to be thin have greater elevations of fasting insulin and poorer insulin sensitivity above and beyond the effect of fat mass. Future research is warranted to elucidate the mechanisms responsible for this relationship.
