Firing patterns of human genioglossus motor units during voluntary tongue movement
Firing patterns of human genioglossus motor units during voluntary tongue movement
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DOI：
10.1152/jn.00737.2006
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发表时间：
2007-01-01
影响因子：
2.5
通讯作者：
Fuglevand, Andrew J.
中科院分区：
文献类型：
--
作者：
Bailey, E. Fiona;Rice, Amber D.;Fuglevand, Andrew J.
舌自主运动过程中颏舌肌运动单位的放电模式。J Neurophysiol 97：933 - 936，2007. 2006年10月4日首次出版; doi：10.1152/jn. 00737.2006.舌头参与一系列复杂的口腔行为，包括咀嚼、吞咽、呼吸和言语。以往的人类舌肌电研究主要集中在舌肌活动及其在维持上呼吸道通畅中的作用。值得注意的是，人类舌下神经运动单位的活动没有被研究在执行自愿演习。我们使用钨微电极在10名健康受试者的颏舌肌中记录了单个运动单位的活动，这些受试者同时进行缓慢的舌头伸出和静态握持动作。舌的位移由通过定制杠杆臂耦合到舌面的等张换能器检测。对于突出试验，招募时的发射率为13.1 +/- 3 Hz，并急剧增加至平均24 +/- 6 Hz，通常舌突出度增加非常适度。对于静态保持任务，平均放电率为16.1 +/-4 Hz，这相对于肢体运动单元是令人惊讶的高。穗间距的平均变异系数接近20%（范围，10-28%）。这些是第一次记录他们的类型获得的人类受试者，并提供了初步的一瞥舌下运动神经元的自愿控制，在舌头运动可能是由运动皮层的活动煽动。
Firing patterns of human genioglossus motor units during voluntary tongue movement. J Neurophysiol 97: 933 - 936, 2007. First published October 4, 2006; doi:10.1152/jn. 00737.2006. The tongue participates in a range of complex oromotor behaviors, including mastication, swallowing, respiration, and speech. Previous electromyographic studies of the human tongue have focused on respiratory-related tongue muscle activities and their role in maintaining upper airway patency. Remarkably, the activities of human hypoglossal motor units have not been studied during the execution of voluntary maneuvers. We recorded single motor unit activity using tungsten microelectrodes in the genioglossus muscle of 10 healthy human subjects performing both slow tongue protrusions and a static holding maneuver. Displacement of the tongue was detected by an isotonic transducer coupled to the lingual surface through a customized lever arm. For protrusion trials, the firing rate at recruitment was 13.1 +/- 3 Hz and increased steeply to an average of 24 +/- 6 Hz, often with very modest increases in tongue protrusion. For the static holding task, the average firing rate was 16.1 +/- 4 Hz, which is surprisingly high relative to limb motor units. The average coefficient of variation of interspike intervals was similar to 20% (range, 10-28%). These are the first recordings of their type obtained in human subjects and provide an initial glimpse into the voluntary control of hypoglossal motoneurons during tongue movements presumably instigated by activity in the motor cortex.