Induction of sister chromatid exchanges (SCE) in G0 lymphocytes by plutonium-238 alpha-particles.
Induction of sister chromatid exchanges (SCE) in G0 lymphocytes by plutonium-238 alpha-particles.
复制标题
钚 238 α 粒子在 G0 淋巴细胞中诱导姐妹染色单体交换 (SCE)。
DOI：
--
复制
发表时间：
1988
期刊：
影响因子：
--
通讯作者：
J. R. Savage
中科院分区：
文献类型：
--
作者：
S. Aghamohammadi;D. T. Goodhead;J. R. Savage
用钚-238 α粒子和X射线照射人G 0淋巴细胞，以研究姐妹染色单体交换（SCE）的产生。α-粒子产生SCE的显着增加，这种升高是更显着时，分离的淋巴细胞照射。X射线照射没有引起SCE的任何显着增加。因此，该系统中α粒子诱导SCE的相对生物学效应（RBE）是不确定的，实际上是无限的。
Irradiation of human G0 lymphocytes with plutonium-238 alpha-particles and X-rays was performed to investigate the production of sister chromatid exchanges (SCE). Alpha-particles produce a significant increase in SCE and this elevation is more significant when separated lymphocytes are irradiated. X-ray irradiation did not induce any significant increase in SCE. Therefore the relative biological effectiveness (RBE) for the induction of SCE by alpha-particles in this system is undefined and effectively infinite.