Concentrated Bioshell Calcium Oxide (BiSCaO) Water Kills Pathogenic Microbes: Characterization and Activity
Concentrated Bioshell Calcium Oxide (BiSCaO) Water Kills Pathogenic Microbes: Characterization and Activity
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DOI：
10.3390/molecules25133001
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发表时间：
2020-07-01
期刊：
影响因子：
4.6
通讯作者：
Yokoe, Hidetaka
中科院分区：
文献类型：
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作者：
Nakamura, Shingo;Ishihara, Masayuki;Yokoe, Hidetaka
生物贝壳氧化钙(BiSCaO)具有除臭性能和广泛的杀菌活性。在这项研究中，我们研究了BiSCaO水用于这一目的的可能性。BiSCaO水是在清水中加入10wt%的BiSCaO，然后将上清液轻轻收集在瓶子中制成的。将相同体积的清水轻轻倒入BiSCaO沉淀物中，然后将上清液轻轻收集到瓶子中；这一过程重复50次。制得的BiSCaO水含有纳米颗粒(约400-800 nm)，由较小的纳米颗粒(100-200 nm)组成，无色透明，pH>；12.7。体外试验表明，BiSCaO水在15min内对甲型H1N1流感病毒和猫杯状病毒、大肠埃希氏菌NBRC 3972和O-157：H7、铜绿假单胞菌、沙门氏菌和金黄色葡萄球菌的杀灭率均在99.9%以上。我们比较了BiSCaO水与乙醇、BiSCaO、BiSCa(OH)(2)悬浮液、聚维酮碘、NaClO、BiSCaO分散体和胶体分散体等杀菌剂的除臭活性和杀菌效果。结果表明，BiSCaO水是一种对病原菌和病毒(包括包膜病毒和非包膜病毒)具有良好的除臭和消毒活性的强效剂。
Bioshell calcium oxide (BiSCaO) exhibits deodorizing properties and broad microbicidal activity. In this study, we examined possible utility of BiSCaO Water for that purpose. BiSCaO Water was prepared by adding 10 wt% BiSCaO to clean water and gently collecting the supernatant in a bottle. The same volume of clean water was gently poured onto the BiSCaO precipitate and the supernatant was gently collected in a bottle; this process was repeated fifty times. The produced BiSCaO Water contained nanoparticles (about 400-800 nm) composed of smaller nanoparticles (100-200 nm), and was colorless and transparent, with a pH > 12.7. In vitro assays demonstrated that BiSCaO Water eliminated more than 99.9% of influenza A (H1N1) andFeline calicivirus, Escherichia colisuch as NBRC 3972 and O-157:H7,Pseudomonas aeruginosa,Salmonella,andStaphylococcus aureuswithin 15 min. We compared BiSCaO Water with the other microbicidal reagents such as ethanol, BiSCaO, BiSCa(OH)(2)suspensions, povidone iodine, NaClO, BiSCaO dispersion and colloidal dispersion with respect to deodorization activity and microbicidal efficacy. The results showed that BiSCaO Water was a potent reagent with excellent deodorization and disinfection activities against pathogenic bacteria and viruses (including both enveloped and nonenveloped viruses).