Harnessing brain waves: a review of brain magnetic resonance elastography for clinicians and scientists entering the field.
Harnessing brain waves: a review of brain magnetic resonance elastography for clinicians and scientists entering the field.
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利用脑波：进入该领域的临床医生和科学家的脑磁共振弹性成像回顾。
DOI：
10.1259/bjr.20200265
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发表时间：
2021-03-01
期刊：
影响因子：
--
通讯作者：
Huston Iii J
中科院分区：
文献类型：
--
作者：
Arani A;Manduca A;Ehman RL;Huston Iii J
脑磁共振弹性成像（MRE）是一种能够准确、无创地测量活人大脑的机械特性的成像技术。最近的研究表明，MRE 有潜力为颅内肿瘤、脱髓鞘疾病、神经退行性疾病、颅内压升高和功能状态改变的患者提供临床有用的信息。本次综述的目的是：(1) 概述在患者群体中通过脑 MRE 获得的测量类型，(2) 调查目前用于实现这些测量的工具，以及 (3) 强调基于脑 MRE 的定量生物标志物，这些生物标志物在未来 5 至 10 年内最有可能被应用于临床。描述了 MRE 方法策略的具体细节，从波生成到材料参数估计。描述了 MRE 在描述和计划颅内肿瘤手术切除以及评估由弥漫性神经系统疾病和颅内压改变引起的脑硬度弥漫性变化方面的潜在临床作用。此外，还介绍了功能性 MRE 的新兴技术、人工智能在 MRE 中的作用以及 MRE 在一般神经科学研究中的前景应用。
Brain magnetic resonance elastography (MRE) is an imaging technique capable of accurately and non-invasively measuring the mechanical properties of the living human brain. Recent studies have shown that MRE has potential to provide clinically useful information in patients with intracranial tumors, demyelinating disease, neurodegenerative disease, elevated intracranial pressure, and altered functional states. The objectives of this review are: (1) to give a general overview of the types of measurements that have been obtained with brain MRE in patient populations, (2) to survey the tools currently being used to make these measurements possible, and (3) to highlight brain MRE-based quantitative biomarkers that have the highest potential of being adopted into clinical use within the next 5 to 10 years. The specifics of MRE methodology strategies are described, from wave generation to material parameter estimations. The potential clinical role of MRE for characterizing and planning surgical resection of intracranial tumors and assessing diffuse changes in brain stiffness resulting from diffuse neurological diseases and altered intracranial pressure are described. In addition, the emerging technique of functional MRE, the role of artificial intelligence in MRE, and promising applications of MRE in general neuroscience research are presented.
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影响因子：
5
作者：
ElSheikh, Mona;Arani, Arvin;Huston, John, III
通讯作者：
Huston, John, III
影响因子：
6.3
作者：
Hetzer, Stefan;Dittmann, Florian;Sack, Ingolf
通讯作者：
Sack, Ingolf
DOI：
10.1016/j.jmbbm.2016.03.005
发表时间：
2016-06-01
影响因子：
3.9
作者：
Anderson, Aaron T.;Van Houten, Elijah E. W.;Johnson, Curtis L.
通讯作者：
Johnson, Curtis L.
朝向大脑解剖结构的弹性图。
影响因子：
3.7
作者：
Guo J;Hirsch S;Fehlner A;Papazoglou S;Scheel M;Braun J;Sack I
通讯作者：
Sack I
影响因子：
4.4
作者：
Glaser, Kevin J.;Manduca, Armando;Ehman, Richard L.
通讯作者：
Ehman, Richard L.