Body mass index and mortality in 'healthier' as compared with 'sicker' haemodialysis patients: results from the Dialysis Outcomes and Practice Patterns Study (DOPPS)
Body mass index and mortality in 'healthier' as compared with 'sicker' haemodialysis patients: results from the Dialysis Outcomes and Practice Patterns Study (DOPPS)
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DOI：
10.1093/ndt/16.12.2386
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发表时间：
2001-12-01
影响因子：
6.1
通讯作者：
Young, EW
中科院分区：
文献类型：
--
作者：
Leavey, SF;McCullough, K;Young, EW
背景。身体质量指数（BMI）较低的血液透析（HD）患者具有较高的相对死亡风险（RR），与种族无关。然而，只有接受HD治疗的亚裔美国人被发现有较高BMI的RR升高。患有HD的亚裔美国人比其他种族群体“更健康”（即总体存活率更高）。我们假设，在各种其他“健康”的HD患者亚组中，死亡风险的增加可能与高BMI有关。前瞻性透析结果和实践模式研究（DOPPS）提供了基线人口统计学。美国和欧洲9714例HD患者的合并症和BMI数据。德国，意大利，西班牙和英国)1996-2000年。使用多变量生存分析，我们评估了HD亚群中bmi与死亡率的关系，这些亚群由大陆、种族（黑人和白人）、性别、疾病严重程度的分位数（基于合并症条件和血清白蛋白浓度得出的评分）、年龄(
Background. Haemodialysis (HD) patients with lower body mass index (BMI) have a higher relative mortality risk (RR), irrespective of race. However, only Asian Americans treated with HD have been found to have an elevated RR with higher BMI. Asian Americans on HD are 'healthier' than other race groups (i.e. have better overall survival). We hypothesized that an increased mortality risk might be associated with high BMI in a variety of other 'healthier' subgroups of HD patients.Methods. The prospective Dialysis Outcomes and Practice Patterns Study (DOPPS) provided baseline demographic. comorbidity and BMI data on 9714 HD patients in the US and Europe (France. Germany, Italy, Spain, and the UK) from 1996-2000. Using multivariate survival analyses, we evaluated BMI-mortality relationships in HD subpopulations defined by continent, race (black and white), gender, tertiles of severity of illness (based on a score derived from comorbid conditions and serum albumin concentration), age (