SCOP: a structural classification of proteins database

SCOP: a structural classification of proteins database
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DOI:
10.1093/nar/27.1.254
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发表时间:
1999-01-01
影响因子:
14.9
通讯作者:
Chothia, C
Chothia, C
中科院分区:
生物学2区
文献类型:
--
作者:
Hubbard, TJP;Ailey, B;Chothia, C

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蛋白质结构分类(SCOP)数据库提供了所有已知蛋白质结构之间关系的详细和全面的描述。分类是在层次上:前两个层次,家庭和超家庭,描述近和远的进化关系;第三,折叠,描述几何关系。到目前为止,进化关系与蛋白质的物理和化学关系之间的区别是这个数据库独有的特征。该数据库可用作校准序列搜索算法和生成蛋白质结构的群体统计数据的数据源。该数据库及其相关文件可从URL http://scop.mrc-lmb.cam.ac.uk/scop/镜像的多个WWW站点免费访问。
The Structural Classification of Proteins (SCOP) database provides a detailed and comprehensive description of the relationships of all known proteins structures. The classification is on hierarchical levels: the first two levels, family and superfamily, describe near and far evolutionary relationships; the third, fold, describes geometrical relationships. The distinction between evolutionary relationships and those that arise from the physics and chemistry of proteins is a feature that is unique to this database, so far. The database can be used as a source of data to calibrate sequence search algorithms and for the generation of population statistics on protein structures. The database and its associated files are freely accessible from a number of WWW sites mirrored from URL http://scop.mrc-lmb.cam.ac.uk/scop/.