A new sialyloligosaccharide from human milk: isolation and characterization using anti-oligosaccharide antibodies.
A new sialyloligosaccharide from human milk: isolation and characterization using anti-oligosaccharide antibodies.
复制标题
人乳中的一种新唾液酸寡糖:使用抗寡糖抗体进行分离和表征。
DOI:
10.1016/0003-9861(84)90198-x
复制
发表时间:
1984
影响因子:
3.9
通讯作者:
Smith,DF
中科院分区:
文献类型:
--
作者:
Prieto,PA;Smith,DF
A previously undescribed Sialyloligosaccharide has been isolated from human milk using a specific anti-sialyloligosaccharide antibody. Structural studies of the radiolabeled oligosaccharide by enzyme degradation and binding by specific anti-oligosaccharide sera are consistent with the following structure: The oligosaccharide is present only in milk from donors who secrete A, B, or H blood group substances; this is consistent with the requirement of at least one copy of the Se (Secretor) gene necessary for the synthesis of oligosaccharides with Fucα1–2Gal … linkages.