Recent advances in the synthesis of C-oligosaccharides.
Recent advances in the synthesis of C-oligosaccharides.
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DOI：
10.2174/156802605774643033
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发表时间：
2005
影响因子：
3.4
通讯作者：
Xuejun Yuan;R. Linhardt
中科院分区：
文献类型：
--
作者：
Xuejun Yuan;R. Linhardt
本文综述了近年来分解代谢稳定的模拟糖c -寡糖的合成研究进展。这些化合物是天然存在的o -寡糖的合成类似物，其中糖苷间的氧已被亚甲基取代。本文将c -低聚糖的合成方法分为阴离子法、阳离子法、还原性糖基钐化学、环化法和自由基化学。
This paper reviews the recent advances in the synthesis of catabolically stable sugar mimetics, C-oligosaccharides. These compounds are synthetic analogs of the naturally occurring O-oligosaccharides, in which the interglycosidic oxygen has been replaced by a methylene group. This review is organized in terms of chemistry used to assemble C-oligosaccarides under the sub-headings: anionic approaches, cationic methods, reductive glycosyl samarium chemistry, cyclization methodology, and free radical chemistry.