EFFECTS OF LARGE VESSELS IN FUNCTIONAL MAGNETIC-RESONANCE-IMAGING AT 1.5 T
EFFECTS OF LARGE VESSELS IN FUNCTIONAL MAGNETIC-RESONANCE-IMAGING AT 1.5 T
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DOI：
10.1002/ima.1850060216
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发表时间：
1995-06-01
影响因子：
3.3
通讯作者：
VANGELDEREN, P
中科院分区：
文献类型：
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作者：
DUYN, JH;FRANK, JA;VANGELDEREN, P
为了进一步研究大血管对1.5 T时功能性磁共振成像生成的激活图的影响，我们使用多种专用FLASH和回声平面成像（EPI）扫描技术研究了人类视觉和运动皮层的激活。进行切片和体积扫描，以评估T-2*效应、流内效应和相移效应的相对贡献，特别是在较大血管内部和周围（直径约1mm）。单片FLASH研究中的对比机制似乎主要对这些大血管内的血流和相效应敏感，它们的相对贡献取决于实验参数和血管几何形状。梯度回声EPI研究中的造影剂机制主要受大血管周围组织水（以及较小程度的脑脊液）中的T-2*效应支配。(C) 1995 John Wiley & Sons, Inc.；
To further investigate the effects of large vessels on the activation maps generated with functional magnetic resonance imaging at 1.5 T, we studied activation of the human visual and motor cortex using a multitude of dedicated FLASH and echo-planar imaging (EPI) scanning techniques. Both slice and volume scans were performed to assess relative contributions of T-2* effects, in-flow, and phase-shift effects, specifically within and around the larger vessels (around 1 mm in diameter). The contrast mechanism in single-slice FLASH studies appeared to be predominantly sensitive to in-flow and phase effects of the blood water within these larger vessels, and their relative contributions were dependent on experimental parameters and vascular geometry. The contrast mechanism in gradient echo EPI studies was governed predominantly by T-2* effects in tissue water (and to a lesser extent cerebrospinal fluid) surrounding the larger vessels. (C) 1995 John Wiley & Sons, Inc.