Synthesis of ZnO nanoparticles supported on mesoporous SBA-15 with coordination effect -assist for anti-bacterial assessment
Synthesis of ZnO nanoparticles supported on mesoporous SBA-15 with coordination effect -assist for anti-bacterial assessment
复制标题
具有配位效应的介孔SBA-15负载ZnO纳米颗粒的合成-辅助抗菌评估
DOI：
10.1016/j.colsurfb.2019.05.055
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发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Zhou Hongjun
中科院分区：
文献类型：
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作者：
Wen Hongjian;Zhou Xinhua;Shen Zhichuan;Chen Huayao;Hao Li;Zhou Hongjun
将聚乙烯亚胺（PEI）固定在SBA-15上，得到聚乙烯亚胺改性二氧化硅PEI@SBA-15s （PEI@SBA-1.0, PEI@SBA-1.5, PEI@SBA-2.0）。在PEI的配合下，将锌离子浸渍在PEI@SBA-15s上，然后将Zn2+-PEI@SBA-15s在550℃下煅烧，得到负载在介孔二氧化硅上的纳米氧化锌ZnO-SBA-15s （ZnO-SBA-1.0、ZnO-SBA-1.5和ZnO-SBA-2.0）。负载zno的SBA-15的抑菌活性为；然后，通过抑制区和酶标记法进行评价。结果证实PEI中亚胺基的配位能力有助于在浸渍过程中吸附更多的锌离子，从而使SBA-15表面承载更多的纳米zno。改性没有改变SBA-15二维六边形相的细观结构和有序性。在PEI:SBA-15的质量比为1.0:1、1.5:1和2.0:1时，采用电感耦合等离子体发射光谱法测定ZnO-SBA-1.0、ZnO-SBA-1.5和ZnO-SBA-2.0的锌元素浓度（wt.%）分别为2.5、2.56和3.5%。对SBA-15、ZnO-SBA-0、ZnO-SBA-1.0、ZnO-SBA-1.5和ZnO-SBA-2.0的抑制大小分别为0、1.14±0.01、2.56±0.01、2.58±0.01和2.69±0.02 cm。与空白SBA-15相比，ZnO- sba -15s抑制大肠杆菌的生长呈ZnO剂量依赖性。
Polyethyleneimine (PEI) was immobilized on SBA-15 for obtaining polyethyleneimine-modified silica PEI@SBA-15s (PEI@SBA-1.0, PEI@SBA-1.5, and PEI@SBA-2.0). With the coordination from PEI, zinc ions were impregnated on the PEI@SBA-15s, and then, Zn2+-PEI@SBA-15s were calcined at 550 ℃ to obtain the nano zinc oxide loaded on the mesoporous silica, ZnO-SBA-15s (ZnO-SBA-1.0, ZnO-SBA-1.5, and ZnO-SBA-2.0). The anti-bacterial activity of ZnO-loaded SBA-15 was; thereafter, assessed by the zone of inhibition and enzyme labeling methods. The results confirmed that the coordination ability of the imino groups in PEI helped adsorb more zinc ions during the process of impregnation so that more nano-ZnO could be supported on the surface of SBA-15. The modification did not change the mesostructure of the two-dimensional hexagonal phase and orderliness of SBA-15. At the mass ratio of PEI:SBA-15 = 1.0:1, 1.5:1, and 2.0:1, the concentration of zinc element (wt.%) was measured by inductively coupled plasma optical emission spectrometry as 2.5, 2.56, and 3.5% for ZnO-SBA-1.0, ZnO-SBA-1.5, and ZnO-SBA-2.0, respectively. The size of inhibition of SBA-15, ZnO-SBA-0, ZnO-SBA-1.0, ZnO-SBA-1.5, and ZnO-SBA-2.0 were 0, 1.14 ± 0.01, 2.56 ± 0.01, 2.58 ± 0.01, and 2.69 ± 0.02 cm, respectively. ZnO-SBA-15s suppressed the growth of Escherichia coli compared to blank SBA-15 in a ZnO dose-dependent manner.