Botulinum-A toxin: an exciting new treatment option for prostatic disease.

Botulinum-A toxin: an exciting new treatment option for prostatic disease.
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A 型肉毒杆菌毒素:前列腺疾病的一种令人兴奋的新治疗选择。

DOI:
10.1111/j.1742-1241.2006.01180.x
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发表时间:
2006
期刊:
International journal of clinical practice. Supplement
影响因子:
--
通讯作者:
Chancellor,MB
Chancellor,MB
中科院分区:
--
文献类型:
--
作者:
Thomas,CA;Guercini,F;Chuang,Y-C;Chancellor,MB

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Recently, botulinum neurotoxin type A (BoNT‐A) application in the lower urinary tract has been extended to prostate disorders and we would like to review the literature on the mechanisms of action and clinical efficacy of BoNT‐A treatment in the prostate. The information was gathered from MEDLINE, abstracts from recent urological meetings and from personal experience. BoNT has demonstrated promising preliminary results for male prostatic disease and translational research suggests a novel mechanism of action of BoNT in the prostate. It is important to remember that the application of BoNT in the prostate is not approved by the regulatory agencies and caution should be applied until larger randomised clinical studies are completed.
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