AUTORADIOGRAPHIC STUDIES ON TURNOVER TIME AND PROTEIN SYNTHESIS IN PIG EPIDERMIS.
AUTORADIOGRAPHIC STUDIES ON TURNOVER TIME AND PROTEIN SYNTHESIS IN PIG EPIDERMIS.
复制标题
猪表皮周转时间和蛋白质合成的放射自显影研究。
DOI：
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发表时间：
1965
影响因子：
6.5
通讯作者：
G. Weinstein
中科院分区：
文献类型：
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作者：
G. Weinstein
表皮在基底细胞层经历不断的细胞更新，以取代角质层细胞的持续损失。Leblond和Walker(1)回顾了关于正常表皮周转时间的研究，发现不同哺乳动物的周转时间在13-100天之间。最近，Rothberg等(2)通过测量静脉注射甘氨酸- c14后采集的同位素标记角质层蛋白（角蛋白）来测定人表皮的周转期。他们报告正常表皮的周转期为26-28天。
The epidermis undergoes constant cellular renewal at the basal cell layer to replace the continual loss of cells by the stratum corneum. Leblond and Walker (1) reviewed studies on turnover timesj of normal epidermis and found that they ranged from 13-100 days in different mammals. Recently, Rothberg, et al (2) determined the turnover time of human epidermis by measuring isotopically labeled stratum corneum protein (keratin) collected after the intravenous injection of glycine-C14. They reported a turnover time of normal epidermis to be 26-28 days.