What we do and don't know about 'race', 'ethnicity', genetics and health at the dawn of the genome era
What we do and don't know about 'race', 'ethnicity', genetics and health at the dawn of the genome era
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DOI：
10.1038/ng1436
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发表时间：
2004-11-01
期刊：
影响因子：
30.8
通讯作者：
Collins, FS
中科院分区：
文献类型：
--
作者：
Collins, FS
要真正了解疾病风险，就必须彻底检查根本原因。“种族”和“民族”是定义不明确的术语，是疾病病因中多种环境和遗传因素的有缺陷的替代者，这些因素包括祖籍地理来源、社会经济地位、教育和获得医疗保健的机会。研究必须超越这些脆弱和不完美的代理关系，以确定影响健康的更接近的因素。
A true understanding of disease risk requires a thorough examination of root causes. 'Race' and 'ethnicity' are poorly defined terms that serve as flawed surrogates for multiple environmental and genetic factors in disease causation, including ancestral geographic origins, socioeconomic status, education and access to health care. Research must move beyond these weak and imperfect proxy relationships to define the more proximate factors that influence health.