Chemical and Radiation-Associated Jaw Lesions.
Chemical and Radiation-Associated Jaw Lesions.
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DOI：
10.1016/j.cden.2015.08.009
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发表时间：
2016-01-01
影响因子：
--
通讯作者：
Akintoye, Sunday O
中科院分区：
文献类型：
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作者：
Omolehinwa, Temitope T;Akintoye, Sunday O
颌骨坏死是全世界主要的公共卫生问题。使用放射疗法治疗头颈癌以及抗骨吸收剂和抗血管生成剂增加了其发病率。与其他类型的骨坏死相比，药物相关的颌骨坏死更为常见。尽管有更好的治疗计划和屏蔽以尽量减少对骨骼的附带损害，放射性骨坏死还是会发生。其他相关的坏死性病变是继发于使用娱乐性药物和类固醇的。本文提供了有关这些不同类型的骨坏死的全面信息；为读者提供放射学诊断标准和骨坏死病理生理学最新理论。
Osteonecrosis of the jaw is a major public health concern throughout the world. Use of radiotherapy for head and neck cancer and bone antiresorptives and antiangiogenic agents have increased its incidence. Medication-related osteonecrosis of the jaw is more common relative to other types of osteonecrosis. Osteoradionecrosis occurs despite better treatment planning and shielding to minimize collateral damage to bone. Other related necrotic lesions are secondary to usage of recreational drugs and steroids. This article provides comprehensive information about these different types of bone necrosis; provides the readers with radiographic diagnostic criteria and updates on current theories on pathophysiology of osteonecrosis.