Low cytotoxicity porous Nd2(SiO4)3 nanoparticles with near infrared excitation and emission
Low cytotoxicity porous Nd2(SiO4)3 nanoparticles with near infrared excitation and emission
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DOI：
10.1088/0957-4484/22/18/185703
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发表时间：
2011-03
期刊：
影响因子：
3.5
通讯作者：
Xian-Hua Zhang;D. Zeng;Lei Zhang;Haomiao Zhu;Guang-hui Jin;Zhaoxiong Xie;Xueyuan Chen;Junyong Kang;Lan-Sun Zheng
中科院分区：
文献类型：
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作者：
Xian-Hua Zhang;D. Zeng;Lei Zhang;Haomiao Zhu;Guang-hui Jin;Zhaoxiong Xie;Xueyuan Chen;Junyong Kang;Lan-Sun Zheng
通过可控路线成功合成了多孔 Nd2(SiO4)3 纳米颗粒。这种硅酸盐纳米颗粒可以被近红外（NIR）辐射（808 nm）激发，并在室温下引发近红外发射（1066 nm）。通过监测 1066 nm 发射，确定长寿命发光寿命为 19.5 µs。这些具有适当直径（<100 nm）的近红外纳米颗粒适合细胞测定。 MTT分析表明多孔Nd2(SiO4)3纳米粒子的细胞毒性非常低。因此，这些多孔硅酸盐纳米颗粒是潜在的生物安全高性能近红外生物标记材料。
Porous Nd2(SiO4)3 nanoparticles were successfully synthesized by a controlled route. This kind of silicate nanoparticle could be excited by near-infrared (NIR) radiation (808 nm) and triggered a NIR emission (1066 nm) at room temperature. By monitoring the 1066 nm emission, the long-lived luminescent lifetime was determined to be 19.5 µs. These NIR nanoparticles with appropriate diameters (<100 nm) were suitable for cell assays. MTT assays showed that the cytotoxicity of the porous Nd2(SiO4)3 nanoparticles was very low. Therefore, these porous silicate nanoparticles are potential biosafe high-performance NIR biolabeling materials.