Donepezil treatment of patients with severe Alzheimer's disease in a Japanese population: Results from a 24-week, double-blind, placebo-controlled, Randomized trial
Donepezil treatment of patients with severe Alzheimer's disease in a Japanese population: Results from a 24-week, double-blind, placebo-controlled, Randomized trial
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DOI：
10.1159/000122961
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发表时间：
2008-01-01
影响因子：
2.4
通讯作者：
Ohbayashi, Toshio
中科院分区：
文献类型：
--
作者：
Homma, Akira;Imai, Yukimichi;Ohbayashi, Toshio
背景/目标：进行了一项为期24周的随机、平行组、双盲安慰剂对照研究，以评估多奈哌齐治疗重度阿尔茨海默病（AD）的疗效和耐受性。方法：对10例重度AD患者（简易精神状态检查评分1-12分;改良Hachinski缺血评分
Background/ Aims: A 24- week, randomized, parallel-group, double-blind placebo-controlled study was conducted to evaluate the efficacy and tolerability of donepezil in severe Alzheimer's disease ( AD). Methods: Patients with severe AD (Mini- Mental State Examination score 1-12; modified Hachinski Ischemic Score