Exogenous ligand binding property of a heme-DNA coordination complex
Exogenous ligand binding property of a heme-DNA coordination complex
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DOI：
10.1246/cl.2006.126
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发表时间：
2006-01-05
影响因子：
1.6
通讯作者：
Yamamoto, Y
中科院分区：
文献类型：
--
作者：
Ohyama, T;Kato, Y;Yamamoto, Y
发现咪唑作为外源配体与血红素、铁 (III)-原卟啉 IX 复合物和平行 G-四链体 DNA 之间形成的配位复合物中的 Fe3+ 配位，该配位复合物由人端粒的单个重复序列 d(TTAGGG) 组装而成，化学计量比为 1:1，结合常数为 19 M-1。
Imidazole was found to be coordinated, as an exogenous ligand, to Fe3+ in a coordination complex formed between heme, the iron (III)-protoporphyrin IX complex, and a parallel G-quadruplexed DNA assembled from a single repeat sequence of the human telomere, d(TTAGGG), the stoichiometric ratio being 1:1 and the binding constant 19 M-1.