Dyslipidemia and Fatty Liver Disease in Overweight and Obese Children.
Dyslipidemia and Fatty Liver Disease in Overweight and Obese Children.
复制标题
DOI：
10.1155/2018/8626818
复制
发表时间：
2018
影响因子：
3.3
通讯作者：
Elfatih A
中科院分区：
文献类型：
--
作者：
Deeb A;Attia S;Mahmoud S;Elhaj G;Elfatih A
肥胖是一个世界性的问题。它与血脂异常和肝病等发病有关。儿童肥胖症急剧增加，特别是在海湾地区。我们的目的是评估超重和肥胖儿童中血脂异常和脂肪肝疾病（FLD）的患病率，并分析不同人体测量指标与血脂异常和脂肪肝疾病之间的关联。 对肥胖儿童进行的描述性横断面研究。绘制 BMI 百分位数并生成标准化腰围 (WC)。记录代谢综合征家族史。对酶升高的患者进行空腹血脂、肝转氨酶和超声扫描（美国）。定量参数采用描述性统计。 招募了 216 名参与者。平均±SD年龄为10.58±2.996岁。 55.3%患有血脂异常； 11.7% 的人胆固醇高，28.6% 的人甘油三酯高，32.7% 的人低密度脂蛋白高，18.0% 的人高密度脂蛋白低。 51 人 (84%) 的转氨酶升高。所有人均患有肝脏超声检查，其中 43 人患有 FLD。 WC与血脂异常和FLD密切相关（P=0.04 和 0.003）。 血脂异常常见于超重、肥胖儿童。 FLD 在肝转氨酶升高的人群中很常见。 WC 是一种简单的工具，可用于筛查超重和肥胖儿童的血脂异常和 FLD。
Obesity is a worldwide concern. It is associated with morbidity such as dyslipidemia and liver disease. Childhood obesity has dramatically increased, particularly in the Gulf region. We aim to assess the prevalence of dyslipidemia and fatty liver disease (FLD) in overweight and obese children and analyze the association between different anthropometric measures with dyslipidemia and fatty liver disease. A descriptive, cross-sectional study conducted on children referred with obesity. BMI percentiles were plotted and standardized waist circumference (WC) was generated. Family history of metabolic syndrome was recorded. Fasting lipid, liver transaminases, and ultrasound scans (US) for those with elevated enzymes were performed. Descriptive statistics were used for quantitative parameters. 216 participants were recruited. Mean ± SD age was 10.58 ± 2.996 years. 55.3% had dyslipidemia; 11.7% had high cholesterol, 28.6% high triglyceride, 32.7% high LDL, and 18.0% low HDL. 51 (84%) had either elevated transaminases. All had liver US, and 43 had FLD. WC was strongly associated with dyslipidemia and FLD (P=0.04 and 0.003). Dyslipidemia is common in overweight, obese children. FLD is prevalent in those with elevated liver transaminases. WC is an easy tool that can be utilized to screen for dyslipidemia and FLD in overweight and obese children.