The effect of concurrent endometriosis on the prognosis of women with ovarian clear cell or endometrioid carcinoma
The effect of concurrent endometriosis on the prognosis of women with ovarian clear cell or endometrioid carcinoma
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DOI：
10.1002/ijgo.12861
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发表时间：
2019-08-01
影响因子：
3.8
通讯作者：
Kim, Seok Mo
中科院分区：
文献类型：
--
作者：
Ju, U. Chul;Kang, Woo Dae;Kim, Seok Mo
Objectives: To evaluate features of ovarian clear cell carcinoma (CCC) and endometrioid carcinoma (EC) by presence of endometriosis among women with endometriosis-associated ovarian cancer (EAOC).Methods: A retrospective review of the medical records of 578 women diagnosed and treated for ovarian cancer at a university hospital in Korea between July 2004 and December 2016. Clinical and prognostic features of ovarian CCC and EC were compared between women with endometriosis and those without.Results: Ovarian CCC and EC were diagnosed at an earlier FIGO stage for women with endometriosis than for those without (P=0.033). The 5-year disease-free survival (DFS) and overall survival (OS) were 77.6% vs 65.0% (P=0.038) and 80.3% vs 70.9% (P=0.048), respectively. In univariate analysis, advanced stage, higher grade, bilateral tumors, lymph node metastasis, residual tumor greater than 1 cm, and non-concurrent endometriosis were related to shorter DFS and OS; however, residual tumor greater than 1 cm was the only independent predictor in multivariate analysis (DFS: hazard ratio (HR), 9.83; 95% confidence interval (CI), 4.84-19.93; OS: HR, 5.07; 95% CI, 2.33-11.03). No factors affected survival after stratificati on by stage.Conclusion: No association was found between the presence of endometriosis and the prognosis of ovarian CCC or EC.
